Here’s the main thing as I understand it, Wyze’s GDC (Garage Door Controller) doesn’t natively install to work with Garage Doors that use the Security+ 2.0 protocol.
So if it has a round yellow learning button, then it is technically not compatible. The Security+ protocol is a proprietary standard for I believe Liftmaster/Chamberlain, making it harder to support (probably because they want everyone to either use “MyQ” system, or pay them more money to support their proprietary protocol).
Having said that, I have an “incompatible” garage door opener using the Security+ 2.0 protocol and a round yellow learning button, BUT I just wired the Wyze GDC to a Garage door remote control instead of directly to the Opener, and POOF! It works for an “incompatible” Garage door too. I followed the steps in this thread:
Using that method, basically every Garage Door Opener is compatible If you’re willing to use a remote instead.