Thermostat - no heat

I just received two thermostats for my home with two heat pumps. They look great, but I’m having difficulties getting them to work. They are connected using a 5 wire strand as outlined below.

Challenge 1: thermostat won’t power on at one location.
The old thermostat worked fine. I tried connecting both of the new Wyze thermostats and neither powers on. They both power on at a different thermostat location in my home so this tells me it’s not the thermostat. Any idea what it could be?

Challenge 2: no heat.
My original thermostats had a combined terminal for the white wire, W1/OB, and the wyze thermostat does not. I separately tried connecting the wire to O/B and W1 to no avail.

ORIGINAL
White: W1 / O/B
Yellow: Y1
Green: G
Red: R
Blue: C

WYZE
White: W1 or O/B
Yellow: Y1
Green: G
Red: RC
Blue: C

How can I get the heat working?