Can Thermostat auto switch between Heat and Cool

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Found this topic might be very close to my question. I have an old Honeywell Q539A thermostat (round mercury type with a switch for cooling, off, or heating). It has 6 wires: W, G, Y, R, O and B. The first four seem easy to do, however, it is hard to know how O and B are connected. According to the manual, O(range) is for cooling damper motor, and B(lue) is for heating damper motor. Can WYZE new thermostat be used to replace my old Honeywell Q539A? I have a transformer in case I don’t have C wire in my current system.