I also had a plantronics wired USB headset with volume and mute controls, and mute always worked. I have a feeling it muted the microphone from within the hardware, not relying on the Operating System.
As I don’t use alexa/siri/google assistant… It would be ideal if the Wyze app could select functionality for the button press. I’d prefer the side button to ONLY function as mute/unmute from within the hardware. Making this a customizable function in the app would support my use case as well as the more AI interested (smart assistant) people.